Wide-field self-referenced optical coherence tomography imaging of the corneal microlayers
Year: 2025
Type: article
Abstract: We present a technique for wide-field OCT imaging of the cornea using self-referenced interference of the anterior corneal surface with the underlying corneal structure. The method employs a custom objective lens that ensures that the probing beam remains nearly perpendicular to the anterior corneal surface, effectively utilizing it as a reference to generate interference. This approach allows for high-resolution, three-dimensional imaging of corneal layers over a 9mm optical zone. Tests on human subjects show the ability of the system to quantify the anterior corneal layer thickness.
Source: Optics Letters
DOI: 10.1364/ol.542289
Authors: Marco Ruggeri, Francesco Pozzo Giuffrida, Ngoc Lan Vy Truong, Jean-Marie Parel, Florence Cabot, Mohamed Abou Shousha, Fabrice Manns, Arthur Ho
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4406304982
