Work

Pulmonary Coinfection of Pneumocystis jirovecii and Aspergillus Species

Year: 2025

Type: article

Study design: Observational Study

Abstract: In this multicenter study of 387 patients who were immunocompromised, 4.5% with invasive pulmonary aspergillosis also had Pneumocystis jirovecii pneumonia. Predictors of coinfection included elevated β-D-glucan and prolonged corticosteroid use. Coinfection correlated with reduced 30-day survival (22% vs 57%), suggesting that early identification and prophylaxis may improve outcomes.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofaf018

Authors: Stefan Hatzl, Christina Geiger, Lisa Kriegl, Andreas Reinisch, Albert Wölfler, Georg Apfaltrer, Markus Keldorfer, Siegfried Rödl, Martin Hoenigl, Philipp Eller, Robert Krause

Institutions: Medical University of Graz, BioTechMed-Graz

Language: English

Topic: Pneumocystis jirovecii pneumonia detection and treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053

Funder: National Institute of Allergy and Infectious Diseases

Award: San Diego Center for AIDS Research (SD CFAR)

OpenAlex ID: W4406435178

FWCI: 2.065

Cites: 14

Cited by: 3

Related to: 10