Year: 2024
Type: article
Abstract: India is the richest biodiversity country, having various varieties of medicinal plants, also connected to resulting medicines, are used in traditional medicine.Diplocyclos palmatus (L.) C. Jeffrey is a wild medicinally significant plant, a member of Cucurbitaceae.The current examination was to observe and record the result of the anticancer study of wild D. palmatus fruit, was subjected to a drying method (tray drying) using ethanolic solvent for extraction.MTT assay and apoptosis study of ethanolic extract of the fruit D. palmatus was tested against HCT116 cell line at various concentrations at three varied period, viz., 24, 48, and 72 h.The outcomes exhibited that ethanolic solvent extract of the fruit of D. palmatus constrained the growth of HCT116 cells of 69.58 µg/ml at IC 50 concentration, respectively.Alternation in the cell morphology also revealed that D. palmatus comprises a few valuable chemical elements extracted using ethanol that can be used further in the management of cancer treatment.
Authors: B. R. Ramya, S. Leelavathi
Institution: University of Mysore
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
Funder: University of Mysore
OpenAlex ID: W4406439880