Molecular identification and therapeutic potential of green seaweed Chaetomorpha antennina (Bory.) Kützing. from coastal area
Year: 2024
Type: article
Abstract: Seaweeds have created a wide impact the pharmaceutical and food industries with its various bioactive substances.Chaetomorpha antennina (Bory.)Kützing, one of the fast growing marine algae which is categorized under green algae, was up to 10 cm tall, with cylindrical or barrel-shaped, unbranched filaments, clinging to rocks and calcareous stones.The primary focus of this research explores the molecular taxonomy, as well as the anti-inflammatory, antibacterial, and antioxidant properties of C. antennina.Seaweed extraction was performed using the ethyl acetate, the phytochemical and biochemical compositions were analyzed along with its total phenolic content.The antibacterial and antioxidant potentials were evaluated by ferric ion reduction power, DPPH radical scavenging and hydrogen peroxide scavenging assays.Moreover, the anti-inflammatory activities were evaluated by denaturing albumin and detection of hemolysis by inducing heat.The biochemical composition such as carbohydrate (39.05%), protein (18.47%), lipid (6.62%) as well as the total phenol content (6.9 µg/ml), DPPH (54.5 µg/ml), FRAP (59.08 µg/ml) and H 2 O 2 (67.47 µg/ml).Albumin denaturation exhibits 74.36 µg/ml, whereas heat induced hemolysis was reported as 54.89 µg/ml and the significant antimicrobial activity was observed.The taxonomic range and molecular characterization of C. antennina using primer and 18S rRNA primer was identified.The study concludes that the crude ethyl acetate extract of C. antennina possesses strong anti-inflammatory and antioxidant properties.The bioactive chemicals found in this green seaweed extracts have the potential to serve as a valuable source for pharmaceutical applications.
Authors: M. Nirmala, R. Priya, K. Gobianand, A. Malarvizhi
Language: English
Subfield: Aquatic Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4406440145