Work

Serum levels of Interleukin-6 in patients chronically infected with hepatitis C virus and their correlation with biochemical liver markers

Year: 2024

Type: article

Abstract: Aims: Estimation of serum levels of interleukin-6 (IL-6) and their correlation with hepatic biochemical parameters in chronic HCV-infected patients versus healthy controls.Methodology and results: Our study consisted of forty-four patients with chronic hepatitis C aged between 16 to 57 years plus 40 healthy controls aged 18-54.Samples were collected from various hospitals in Dohuk governorate.Biochemical liver function markers were assessed using traditional methods according to IFCC instructions.Serum concentrations of IL-6 were automatically evaluated using a Maglumi® CLIA kit.HCV RNA were quantified using the fully automated GeneXpert ® system.Conclusion, significance and impact of study: A significant difference in IL-6 serum levels between HCV-infected patients and healthy controls, plus several significant correlations between this inflammatory cytokine and liver function markers in HCV-infected individuals were found.

Source: Malaysian Journal of Microbiology

DOI: 10.21161/mjm.240047

Authors: Abbas, A. H., AL-Taee, H. A.

Institutions: University of Mosul, Ninevah University

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $110