The women of premenopausal period have features of pathology of endometrium with thyroid pathology
Year: 2024
Type: article
Study design: Observational Study
Abstract: The objective: the women of premenopausal age have a study of nosotropic value of parafunc-tions of thyroid in development of hyperplastic processes of endometrium. Materials and methods. Research of structure and function of thyroid was conducted at pathol-ogy of endometrium. In this research 149 women of premenopausal age, including 39 patients, were plugged with high-differentiated adenocarcinoma of endometrium of the 1а stage (middle age of 50,8±3,0 year; body mass index – 28,2±2,1 kg/m2); 34 patients with atypical hyperplasia of endometrium (middle age of 50,1±2,4 year; body mass index– 28,6±2,3 kg/m2) and 39 patients from glandular-cystic hyperplasia of endometrium (middle age of 48,9±2,2 year; body mass in-dex– 26,6±2,4 kg/m2). A control group was made by 37 healthy women (middle age of 49,1±2,3 year; body mass index– 26,6±2,4 kg/m2).Results.For women the comparable volume of thyroid, and also comparable prevalence of goitre (the volume of thyroid more than 18 mm) and nodules, was determined in the inspected groups. In all cases of found out the nodules of thyroid, speech went about nodes which do not exceed 3 sm in a diameter, and from results of fine-needle aspiration biopsy – about different degree of proliferation of colloid nodular goitre. Information of our research testify to absence statistically meaningful differences of prevalence of different forms of goitre in basic and control groups. In addition, they answer that high prevalence of goitre in the regions of iodic deficit, which all territory of Ukraine behaves to. By ultrasonic re-search of thyroid the different forms of goitre in iodine deficiency regions can be found out in third of the adult population.Conclusions.The results of the conducted researches testify that nosotropic connection absents between the parafunctions of thyroid, different forms of goitre and pathology of endometrium (hyperplastic processes and cancer). The estimation of prevalence of diseases of thyroid among women with hyperplastic processes and cancer of endometrium does not allow to examine viola-tion of its function as factor of risk of development of this pathology. Treatment and supervision of patients with hyperplastic processes and cancer of endometrium must be conducted the diseases of thyroid in obedience to the traditional charts of treatment as combination of two different and not associate diseases.Keywords: pathology of endometrium, thyroid pathology, premenopausal period, diagnostics, treatment.
Author: Iryna Netskar
Institution: Shupyk National Healthcare University of Ukraine
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4406498751