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Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture

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Year: 2025
Type: article
Source: Nature Protocols
DOI: 10.1038/s41596-024-01077-w
Authors: Yan-Ruide Li, Kuangyi Zhou, Derek Lee, Yichen Zhu, Tyler Halladay, Jiaji Yu, Yang Zhou, Zibai Lyu, Ying Fang, Yuning Chen, Sasha Semaan, Lili Yang
Institutions: University of California, Los Angeles, UCLA Jonsson Comprehensive Cancer Center
Language: English

Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: U.S. Department of Defense, California Institute for Regenerative Medicine, University of California, Los Angeles, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles
Awards: G3595327501, HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma, Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer
OpenAlex ID: W4406531152
FWCI: 10.45
Cites: 101
Cited by: 29
Related to: 10
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