Stuck Prosthetic aortic and mitral valves in pregnancy: Thrombolysis with streptokinase
Year: 2024
Type: article
Study design: Case Report
Abstract: Despite improvements in the design of prosthetic heart valves and the use of anticoagulation, stuck valve due to thrombosis remains the most dreaded complication of mechanical heart valve replacement. Discontinuation of anticoagulation during pregnancy due to fear of congenital anomaly as a result of inadequate counseling remains a great challenge. A course of thrombolytic therapy may be considered as a first-line therapy for prosthetic heart valve thrombosis. The safety of thrombolysis in pregnancy is not known. We describe a multigravida with mitral and aortic valve replacement status presenting with acute prosthetic mitral and aortic valve thrombosis and treated successfully with intravenous streptokinase.
Source: Nepal Mediciti Medical Journal
Authors: Biplave Karki, Chitra Raj Sharma, Shristi Joshi, Purna Radha Shrestha
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4406539326