Year: 2024
Type: article
Study design: Observational Study
Abstract: The lining of your airways becomes inflamed and produces mucus, which causes asthma. Along with other symptoms, this inflammation during an attack produces a wheezing or whistling sound as you breathe. The purpose of this study was to measure the serum zinc, calcium, and membrane potential in Owerri's asthmatic individuals. a case control study with 36 asthmatic patients who were receiving care at the General Hospital in Owerri. Serum zinc and serum calcium were measured in fasting venous blood, and the Nernst equation was used to determine membrane potential. The serum zinc was measured by atomic absorption spectrophotometry, while the serum calcium was assessed using the Randox Kit. For statistical analysis, the Independent Student t test was employed.The findings showed that, in comparison to the controls, asthmatic individuals had considerably lower membrane potential, serum zinc, and serum calcium (p<0.05). This study showed that a decline in serum zinc, calcium, and membrane potential may be a key factor in the pathophysiology of asthma. To prevent asthma in Owerri, pregnant women may need to consume higher amounts of these vital trace metals through their diet.
Institution: Madonna University
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4406583419