Work

Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations

Year: 2025

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2025.117293

Authors: Yanping Zeng, Jian Xiao, Li Shi, Yangsha Li, Yuanxin Xu, Jiayun Zhou, Xiao Dong, Haiyang Hou, Chao Zhong, Gang Cheng, Yi Chen, Naixia Zhang, Yanfen Fang, Youhong Hu

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, State Key Laboratory of Drug Research, University of Chinese Academy of Sciences, Nanjing University of Chinese Medicine, Fudan University, Zhejiang Chinese Medical University

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Awards: G3483441230, G7524098099, G8238608989

OpenAlex ID: W4406586526

FWCI: 2.03

Cites: 50

Cited by: 8

Related to: 10