Mid-trimester uterine artery doppler in high risk pregnancies as a predictor of adverse pregnancy outcomes
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objectives: The present study aims at demonstrating an association between abnormal uterine artery doppler waveform in high risk pregnancies at 18-24 weeks of gestation and subsequent development of adverse pregnancy outcomes.Methods: Uterine artery doppler was performed in high risk pregnant women between 18-24 weeks of gestation attending antenatal OPD at ESIC Medical College, Sanathnagar, during the period between March 2018 to February 2019.Presence of pulsatality index (PI) >1.45 or presence of bilateral uterine artery notching was considered as abnormal doppler waveforms.Outcomes measured were preeclampsia, small for gestation (<10 th centile), abruption and intrauterine fetal death.Results: Doppler examination was performed in 115 high risk pregnant women.34.78% had abnormal doppler waveforms.Overall 42 (36.52%)women had Small for gestational age (SGA) babies and 31(26.95%)developed preeclampsia, of which 76% and 70% had abnormal doppler respectively.The sensitivity, specificity, PPV and NPV of PI > 1.45 and bilateral uterine artery notching for predicting preeclampsia were 70%,78.57%,55%and 88% respectively (95% CI 2.3361-8.9923;Pvalue < 0.0001) and that for SGA being 76.19%,89.04%,80%and 86.67% respectively (95% CI 3.3013-10.904;P value <0.0001).Conclusion: Mid-trimester uterine artery doppler waveform analysis performed in high risk women have a high negative predictive value.Hence, women with normal doppler waveforms are unlikely to develop adverse pregnancy outcomes.
Source: The New Indian Journal of OBGYN
Authors: Sravani Mukka, Swathi Emmadisetty
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4406619298