Work

Mutations of variable parts of immunoglobulin heavy chains (IGHV) — assay methodology and recommendations on how to report results

Year: 2024

Type: article

Abstract: Currently, the evaluation of mutational status of variable region of immunoglobulin heavy chain gene (IGHV) makes up one of the key prognostic and predictive tests in patients with chronic lymphocytic leukaemia (CLL), performed before the initiation of the first line therapy. This publication presents the first edition of the Polish recommendations of the Molecular Haematology Section of the Polish Society of Human Genetics (PTGC) concerning the methodology of IGHV mutation status determination and the principles of reporting the results based on the recognised international standards.

Source: Acta Haematologica Polonica

DOI: 10.5603/ahp.103244

Authors: Magdalena Zawada, Marzena Wojtaszewska, Sylwia Czekalska, Paulina Własiuk

Institutions: Szpital Uniwersytecki w Krakowie, University of Rzeszów, Medical University of Lublin

Language: English

Topic: Chronic Lymphocytic Leukemia Research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4406683830

FWCI:

Cites:

Cited by:

Related to: 10