Work

HPV Vaccines: state of the art and novel approaches

Year: 2024

Type: article

Abstract: High-risk genotypes of Human Papillomavirus (HPV) are responsible for cervical cancer and have been shown to be related to the occurrence of other less frequent malignancies (vulva, penis, anus, head and neck). Although in the majority of cases the infection resolves spontaneously, some people fail to clear the virus with an increased risk of neoplastic development. In Italy, HPV vaccination is recommended and offered free of charge to girls and boys from 11 years of age. It is also recommended for immunocompromised patients, individuals with high risk sexual behavior, and women with cervical lesions. The efficacy of HPV vaccination in preventing cervical cancer, especially in uninfected women, has been widely demonstrated. Further advances in technology to improve the efficacy of existing vaccines and the development of novel vaccines are necessary to prevent HPV-associated cancers. The aim of this non-systematic review is to provide an update on the available vaccines and future perspectives for HPV vaccination

Source: Rivista di immunologia ed allergologia pediatrica.

DOI: 10.53151/2531-3916/2024-532

Authors: Giusella M.F. Moscato, Elisabetta Del Duca, Mayla Sgrulletti, Alessandra Beni, Giorgio Costagliola, Maria Felicia Mastrototaro, Davide Montin, Giorgio Ottaviano, Veronica Santilli, Caterina Rizzo, Baldassarre Martire, Viviana Moschese

Institutions: University of Rome Tor Vergata, Policlinico Tor Vergata, University of Pisa, Azienda Ospedaliera Universitaria Pisana, Ospedale Regina Margherita, University of Turin, Bambino Gesù Children's Hospital, Istituti di Ricovero e Cura a Carattere Scientifico

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4406732587

FWCI:

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