Work

Left Atrial Appendage Occlusion: Analyzing Factors for Peridevice Leak with Dual-Occlusive Devices

Year: 2024

Type: article

Abstract: Background: This study examines factors influencing peridevice leak (PDL) in patients treated with the Amplatzer Amulet Occluder for left atrial appendage occlusion (LAAO). Materials and Methods: A retrospective analysis was conducted on 217 patients who underwent successful LAAO with the Amplatzer Amulet Occluder due to atrial fibrillation and anticoagulation contraindications. Follow-up transesophageal echocardiography (TEE) was performed 1-3 months post-procedure to detect PDL and analyze related procedural and anatomical factors. Results: PDL occurred in 42% of patients, predominantly mild (<3 mm). Key factors associated with increased PDL risk included occluder compression <12%, off-axis device positioning, and device size ≥25 mm. Baseline patient characteristics and procedural details did not significantly impact PDL rates. Conclusion: For optimal LAAO outcomes, pre- and periprocedural assessment of LAA size and device positioning is crucial. Ensuring occluder compression above 15% may minimize PDL risks, especially for larger devices.

Source: Clinical Cardiology and Cardiovascular Interventions

DOI: 10.31579/2641-0419/429

Author: Heyder Omran

Institution: St. Marien-Hospital Bonn

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4406907086