Year: 2024
Type: article
Study design: Case Report
Abstract: Background. Reactive arthritis remains one of the significant issues in rheumatological practice. Its relevance is determined by the relatively high incidence rate, delayed etiological diagnosis, and the high frequency of progression to a chronic form of the disease in cases of insufficiently effective treatment. Purpose – o illustrate a clinical case of reactive arthritis in the context of yersiniosis. Materials and Methods. A discharge summary from the medical history of a 32-year-old woman who underwent inpatient treatment in the therapeutic department of the Municipal Nonprofit Enterprise “City Clinical Hospital No. 13,” Kharkiv. Results. The article presents a clinical case of reactive arthritis associated with yersiniosis. The infectious process manifested as a secondary-focal form characterized by prolonged polyarthritis, for which tocilizumab was used as treatment. This case is of interest to internists, general practitioners, family medicine specialists, rheumatologists, and infectious disease specialists due to its unique clinical and immunopathogenic features, as well as the high likelihood of prolonged disease progression and chronicity. Emphasis is placed on the importance of early serological diagnosis and etiological treatment of the disease. Conclusions. 1.Clinical manifestations of yersiniosis are highly polymorphic and require detailed differential diagnosis, as identifying the true etiological factor of reactive arthritis is often challenging and demands attention from physicians of various specialties. 2.The management strategy for this category of patients is highly relevant and problematic, considering that achieving a positive outcome with rational antibiotic therapy in the later stages of the disease is not always effective. 3.Given the etiopathogenetic factors and immune mechanisms underlying the disease and its complications, especially in the later stages, this category of patients requires therapeutic correction and follow-up care involving a wide range of specialists (rheumatologists, cardiologists, gastroenterologists, neurologists, and others).
Authors: T.V. Lukianenko, T.I. Liadova, Ol.V. Volobueva
Institution: V. N. Karazin Kharkiv National University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4406910075