Work

Color-coded galectin fusion proteins as novel tools in biomaterial science

Year: 2025

Type: article

Abstract: . Additionally, we demonstrate the SpyCatcher/SpyTag-mediated immobilization of galectins in microgels, which can serve as a transport platform for localized targeting applications. The proof of concept is provided by the galectin-mediated binding of microgels to colorectal cancer cells.

Source: Biomaterials Science

DOI: 10.1039/d4bm01148a

Authors: Carina Dey, Isabel K. Sommerfeld, Pavla Bojarová, Nikol Kodra, David Vrbata, Miluše Zimolová Vlachová, Vladimír Křen, Andrij Pich, Lothar Elling

Institutions: RWTH Aachen University, DWI – Leibniz Institute for Interactive Materials, Czech Academy of Sciences, Institute of Microbiology, Czech Technical University in Prague, Maastricht University

Language: English

Topic: Galectins and Cancer Biology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: European Commission, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung, Ministerstvo Zdravotnictví Ceské Republiky

Awards: IBZT-01: MiRAGE - Mikrogel-Gegenstrom-Fluss-Reaktor für die automatisierte Glykansynthese mit immobilisierten Enzymen (Teilprojekt B), G3385542441, G415468028, G557173086, G626541477, G7584982096

OpenAlex ID: W4406958189

FWCI:

Cites: 87

Cited by:

Related to: 10