Diabetes and incident stroke and mediation by microvascular dysfunction: Pooled analysis of three population‐based studies
Year: 2025
Type: article
Abstract: BACKGROUNDType 2 diabetes increases the risk of incident stroke. 1 Diabetesrelated stroke is a heterogeneous disease that may be due to various mechanisms, including microvascular dysfunction and damage.2 Cerebral microvascular damage, as quantified by features of cerebral small vessel disease, is more common in type 2 diabetes compared to individuals without diabetes.2 In addition, small vessel disease is an established contributor to stroke.3 However, the extent to which cerebral microvascular dysfunction explains the
Source: Diabetes Obesity and Metabolism
DOI: 10.1111/dom.16217
Authors: Indra L. M. Steens, Yuekai Ji, Sanaz Sedaghat, Jim Pankow, Barbara E. K. Klein, Mary Frances Cotch, Robyn L. McClelland, Kathleen M. Hayden, Timothy M. Hughes, Michael P. Bancks, Alfons J. H. M. Houben, Abraham A. Kroon, Annemarie Koster, Hans Bosma, Tos T. J. M. Berendschot, Bastiaan E. de Galan, Thomas T. van Sloten
Institutions: Maastricht University Medical Centre, Maastricht University, University of Minnesota, University of Wisconsin–Madison, National Institutes of Health, National Eye Institute, University of Washington, Wake Forest University Health Sciences, Wake Forest University, Care and Public Health Research Institute, Radboud University Medical Center, University Medical Center Utrecht
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $5,380
OpenAlex ID: W4406992064