Year: 2024
Type: article
Abstract: Targeted drug delivery has showed great promise using nanocarriers made of liposomes, micelles, polymeric nanoparticles, and others. Nanocarriers' biological interaction can be controlled in the desired way by giving them multifunctionality. Dendriners have easily adjustable surfaces and are highly branched polymers. Other moieties that can actively target specific diseases and improve delivery can be added thanks to the functional groups present in the dendrimers' exterior. Since dendrimers have special structural characteristics, they have become viable drug delivery platforms for nanocamers. The well-defined architecture of dendrimers, which are highly branching, monodisperse, nanosized macromolecules, offers a high degree of surface functionality and internal cavities.Applications for dendrimers (PAMAM, PPI, and polyester) in gene delivery, cancer treatment, and antibiotics have been investigated.This study focusses on the design, functionalisation, and biomedical applications of dendrimer-based nanocarriers, highlighting their potential in personalised medicine and next-generation drug delivery systems.
Language: English
Subfield: Polymers and Plastics
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4407003806