Non-Adherence to Physician’s Recommendations and Associated Risk Factors in Patients Aged 60 Years and Older
Year: 2024
Type: article
Study design: Observational Study
Abstract: AIM. This study aimed to evaluate risk factors of low medication adherence in outpatients aged 60 and over. MATERIALS AND METHODS. A total of 224 participants aged 60 years and over were included in the study. The mean age was 71.2±6.6 years, with 129 (57,6%) being female. General clinical examination, probable frailty screening using the «Age is Not a Hindrance» questionnaire were performed. Medication adherence was assessed using the four-item Morisky Medication Adherence Scale. RESULTS. Adherent and non-adherent patients were comparable in terms of age (p = 0,598), gender (p = 0,563), intake of drug groups, adherence to healthy lifestyle principles, concomitant diseases, with the exception of diabetes mellitus, which was more common (p = 0,037) among non-adherent patients. A negative correlation was established between adherence to treatment and probable frailty (r = −0,24, p < 0,001), diabetes mellitus (= −0,14, p = 0,032). Non-adherence to the treatment regimen was associated with probable frailty (OR 0.26, 95% CI 0.12–0.56; p < 0.001), and the absence of the frailty and diabetes mellitus was associated with high adherence to treatment (OR 4,58, 95% CI 1,24–16,87, p = 0.022). CONCLUSION. Medication non-adherence was found in 38,8% outpatients aged 60 and over. Multimorbid older patients with probable frailty and diabetes mellitus have a high risk of non-adherence to treatment.
Authors: V. N. Larina, E. V. Fedorova, V. I. Lunev, E. N. Sheregova, O. V. Kladovikova
Institution: Pirogov Russian National Research Medical University
Language: English
Subfield: Family Practice
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407034327