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Performing an In Vitro Genome-Wide CRISPR Knockout Screen in Chimeric Antigen Receptor T Cells

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Year: 2025
Type: article
Source: Journal of Visualized Experiments
DOI: 10.3791/67338
Authors: Carli Stewart, Claudia Manriquez Roman, Saad S. Kenderian
Institution: Mayo Clinic
Language: English

Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute
Awards: Simultaneous Thermal and Osmotic Stresses in Tumor Ablation: Imaging and Biology, Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic, Towards Safer and More Effective CART Cell Therapy Through the Modulation of Myeloid Cytokines
OpenAlex ID: W4407061042
FWCI:
Cites: 33
Cited by:
Related to: 10
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