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Systemic Lupus Erythematosus and Dermatomyositis Overlap Syndrome: Diagnostic Challenges and Management Insights

Year: 2025

Type: article

Abstract: We present the case of a 27-year-old female patient who was initially diagnosed with dermatomyositis and later found to have an overlap with systemic lupus erythematosus (SLE). Despite extensive treatment with immunosuppressive medication, the patient experienced multiple deteriorations and treatment-related complications with waxing and waning improvement. This case aims to underscore the challenges involved in diagnosing and managing overlap syndromes and highlights the importance of comprehensive diagnostic workup and multidisciplinary care.

Source: Cureus

DOI: 10.7759/cureus.78424

Authors: Saif-Eddin Dabour, Asmaa Elbenni, Ahmed M Abdel-Megid, Walid Alorfali

Institution: Gdańsk Medical University

Language: English

Topic: Inflammatory Myopathies and Dermatomyositis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4407086264