Work

Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII

Year: 2025

Type: article

Abstract: fly brain, providing an explanation for its neuroprotective effects. Collectively, our study reveals a pharmacologically targetable mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in MPS VII.

Source: Neurobiology of Disease

DOI: 10.1016/j.nbd.2025.106825

Authors: Nishan Mandal, Apurba Das, Rupak Datta

Institution: Indian Institute of Science Education and Research Kolkata

Language: English

Topic: Lysosomal Storage Disorders Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,180