Work

Stromal Vascular Fraction of Adipose Tissue: Prospects for Use in the Treatment of Osteoarthritis and Articular Cartilage Injuries (Literature Review)

Year: 2025

Type: article

Abstract: Summary. Osteoarthritis (OA) is a chronic, progressive, degenerative-dystrophic joint disease primarily caused by damage to the articular cartilage. Conservative pharmacological treatment of OA consists of prescribing nonsteroidal anti-inflammatory drugs, chondroprotectors, hyaluronic acid injections, and therapeutic blockades with glucocorticosteroids. The use of orthobiological agents represents an alternative method in OA treatment. Among the variety of orthobiological approaches, adipose tissue serves as a new and attractive source of stem cells for the treatment of OA. The stromal vascular fraction creates an environment where stem cells can interact and stimulate regeneration.

Source: TERRA ORTHOPAEDICA

DOI: 10.37647/2786-7595-2024-123-4-47-51

Authors: O.O. Kostrub, P.V. Didukh, R.O. Serhiienko, R.I. Blonskyi, I.A. Zasadniuk, S.P. Chornobai, V.A. Podik

Institutions: National Academy of Medical Sciences of Ukraine, State Institution “National Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine”

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4407105576

FWCI:

Cites: 38

Cited by:

Related to: 10