Work

Assessing the efficacy of intraoperative fluorescence imaging for tumor margin identification in breast conserving surgery

Year: 2024

Type: article

Abstract: Breast-conserving surgery (BCS) aims to remove malignant breast tissue while preserving healthy tissue, with clear margins crucial for reducing recurrence and avoiding additional surgeries. This study evaluated the effectiveness of intraoperative fluorescence imaging (IFI) in achieving negative margins compared to standard intraoperative techniques in 100 retrospectively analyzed patients. IFI-assisted BCS achieved negative margins in 88% of cases versus 65% with standard methods (p < 0.001) and significantly reduced re-excision rates (8% vs. 22%, p = 0.002). Long-term recurrence rates over 12 months were similar between the groups (p = 0.145). These findings suggest that IFI enhances margin visualization, reduces re-excisions and serves as a valuable adjunct to traditional techniques in BCS.

Source: Bioinformation

DOI: 10.6026/9732063002001927

Authors: Pritika Gnanasekaran, Niraj Balakrishnan, Navaneeth Ranjith, Rakshana Munusamy, Naveen Bose J

Institutions: Caritas Hospital, Madurai Medical College

Language: English

Topic: Breast Lesions and Carcinomas

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4407107032