Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide gem -Dichlorocyclopropanes are important structural moieties in a range of industrial sectors and have been the focus of considerable interest within the synthetic community over the years. Synthetic methodologies to access gem -dichlorocyclopropanes, however, remain limited. To address this challenge, we report the development of new dichloromethyl(diaryl) sulfonium salts as reagents for the gem -dichlorocyclopropanation of electron-rich olefins via a free dichlorocarbene pathway under mild conditions in yields of up to 70%. This methodology provides access to previously unreported gem -dichlorocyclopropanes.
Source: Organic Letters
Authors: Bethany J. Moore, Darren Willcox
Institution: University of Manchester
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
Award: G7777517809
OpenAlex ID: W4407108810