Work

Initial leads to combat streptogramin resistance generated from X-ray fragment screening against VatD

Year: 2025

Type: article

Source: Structure

DOI: 10.1016/j.str.2025.08.017

Authors: Pooja Asthana, Sonya Lee, Christian M. MacDonald, Ian B. Seiple, James S. Fraser

Institutions: University of California, San Francisco, Scripps Research Institute

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Energy, National Institutes of Health, Office of Science, National Institute of General Medical Sciences, Basic Energy Sciences, Biological and Environmental Research, SLAC National Accelerator Laboratory

Awards: G1767990418, G419881185, Discovering and Manipulating Macromolecular Conformational Ensembles, A Synchrotron Radiation Structural Biology Resource, ALS Efficiently Networking Advanced Beam Line Experiments (ALS-ENABLE), G911061179

OpenAlex ID: W4414163838

FWCI: 0.279

Cites: 34

Cited by: 1

Related to: 10