Work

Leveraging AlphaFold for innovation and sustainable health research in Africa

Year: 2025

Type: article

Abstract: Without addressing the lack of research infrastructure, funding, and supportive science policies, structural biology capacity-building efforts in Africa will continue to be hindered by the persistent challenge of brain drain.

Source: Nature Communications

DOI: 10.1038/s41467-025-56545-y

Authors: Emmanuel Nji, Katharina C. Cramer, Nicolas V. Rüffin, Fatoumata G. Fofana, Walid Heiba, Safiétou Sankhe

Institutions: Kwame Nkrumah University of Science and Technology, Centre for Research in Infectious Diseases, Université des Sciences, des Techniques et des Technologies de Bamako, Alexandria University, Institut Pasteur de Dakar

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Partnerships for the goals

Open Access status: gold

Estimated APC paid: $6,990

Funders: Google, Wellcome Trust, DeepMind, Svenska Forskningsrådet Formas, Vetenskapsrådet

Awards: A network to build structural biology capacity in Africa and support structure-based drug design against malaria, A network to build structural biology capacity in Africa and support structure-based drug design against malaria, A fragment-based screening approach to identify, develop, and characterise novel highly potent and efficacious inhibitors against the malaria parasite uridine diphosphate galactose transporter (UGT)., A fragment-based screening approach to identify, develop, and characterise novel highly potent and efficacious inhibitors against the malaria parasite uridine diphosphate galactose transporter (UGT).

OpenAlex ID: W4407121600

FWCI: 2.548

Cites: 5

Cited by: 10

Related to: 10