Work

The impact of standardization of care for neonates born at 22–23 weeks gestation

Year: 2025

Type: article

Abstract: OBJECTIVE: Determine the impact of standardization of care and counseling on survival and morbidities of neonates born at 22-23 weeks gestation. DESIGN: Retrospective cohort study of 244 neonates born at 22-23 weeks gestation between 2015 and 2023 in a large healthcare system. The primary outcome was survival of neonates receiving intensive care to NICU discharge. Secondary outcomes included morbidities and resource utilization. RESULTS: Neonates born at 22-23 weeks received more intensive care after care standardization (OR 5.4 (95% CI 2.3-12.6), p < 0.0001). Survival remained stable (aOR 0.93 (95% CI 0.32-2.7), p = 0.89) despite more neonates born at 22 weeks receiving intensive care. Resource utilization remained stable. CONCLUSIONS: Standardizing counseling and care increased the provision of antenatal steroids and intensive care for neonates born at 22 weeks gestation. This allowed neonates born at 22 weeks to survive to discharge without increasing morbidity and resource utilization.

Source: Journal of Perinatology

DOI: 10.1038/s41372-025-02214-3

Authors: Faris N. Al Gharaibeh, DonnaMaria E. Cortezzo, Amy T. Nathan, James M. Greenberg

Institutions: Cincinnati Children's Hospital Medical Center, University of Cincinnati, University of Connecticut, Connecticut Children's Medical Center, UConn Health

Language: English

Topic: Infant Development and Preterm Care

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,790