Work

Biologics in Pediatric Idiopathic Nephrotic Syndrome and Other Kidney Diseases—General Principles and Special Considerations

Year: 2025

Type: article

Abstract: Idiopathic nephrotic syndrome (INS) and other pediatric kidney diseases represent significant challenges due to their complex pathogenesis, often involving dysregulated immune responses and renal injury. Biologic therapies, defined as targeted treatments derived from living organisms, have gained traction in managing these conditions, offering a potential shift in therapeutic paradigms. This review examines the current and emerging role of biologics in treating pediatric kidney diseases, focusing on indications, contraindications, adverse effects, therapeutic positioning, and a comparison with alternative immunosuppressive treatments.

Source: Biologics

DOI: 10.3390/biologics5010004

Author: Matjaž Kopač

Institution: Ljubljana University Medical Centre

Language: English

Topic: Renal Diseases and Glomerulopathies

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,207