Bacterial Profile, Antimicrobial Susceptibility Patterns, and Associated Factors of Community-acquired Pneumonia Among Adult Patients in South India: a Cross-sectional Study
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: This study aimed to analyze the bacterial profile, antibiotic sensitivity patterns, and prevalence of multidrug resistance in community-acquired pneumonia patients at a tertiary care hospital in Bangalore, India. Methods: Bacterial isolates were identified using standard microbiological techniques and their antibiotic sensitivity was determined using the Kirby-Bauer disk diffusion method. Results: A total of 215 sputum samples were processed, of which 150 tested positive for bacteria. Klebsiella pneumoniae (32%) was the most common isolate, followed by Acinetobacter spp. (20.66%), and Pseudomonas aeruginosa (16%). Notable antibiotic resistance, particularly against third-generation cephalosporins, was observed, with 17.2% of g-negative isolates exhibiting multidrug resistance, primarily due to Extended-Spectrum Beta-Lactamase (ESBL) production. Conclusion: These findings highlight the need for more effective empirical treatment strategies for CAP.
Author: RAHIL PASHA S. A.
Institution: Sri Devaraj Urs Medical College
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407144032