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Onychomycosis: Unraveling the Role of Dermatophytes in Nail Infections

Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: This study aimed to identify pathogenic fungi that cause onychomycosis and evaluate their clinical presentations and risk factors to enhance management through precise diagnosis and targeted treatment. Methods: The fungi were identified by macroscopic and microscopic morphological features using techniques such as slide cultures, Potassium Hydroxide (KOH) mounts, culture isolation, and Lacto Phenol Cotton Blue (LPCB) staining. Results: 110 nail clippings from patients clinically suspected of onychomycosis were analyzed; 27 had dermatophytic infections. Toenails were involved in 33.8% of the cases, and Distal and Lateral Subungual Onychomycosis (DLSO) was the primary clinical presentation. Trauma was the most common predisposing factor (19%). Conclusion: This study identified dermatophytes as the prime cause of onychomycosis, chiefly affecting toenails with DLSO as the predominant form, and recognized trauma as a key risk factor. Precise identification using traditional diagnostic methods is crucial for targeted treatment and better patient results.
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4407144291
FWCI:
Cites: 15
Cited by:
Related to: 10