Work

Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer

Year: 2025

Type: article

Abstract: T cells in distant tumors in the AIT with αPD-1 group compared to αPD-1 alone. Hence, mitochondria-targeting represents an effective strategy to potentiate the combination of photothermal, chemodynamic, and immune checkpoint blockade therapies for the treatment of metastatic cancer.

Source: Materials Today Bio

DOI: 10.1016/j.mtbio.2025.101542

Authors: Benchao Zheng, Hongbo Wang, Shiyi Zhai, Jiangsheng Li, Kuangda Lu

Institutions: Peking University, National Medical Products Administration, Peking University Cancer Hospital

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,400