Retinal Organoids: Advances in Generation, Development, and Applications – From Stem Cells to Disease Modeling and Regenerative Medicine
Year: 2025
Type: book-chapter
Abstract: Retinal diseases, often caused by the degeneration of light-sensitive cells, pose a significant global health challenge. While current treatments are limited, cell therapy, involving the transplantation of healthy cells, offers hope. Recent advancements in stem cell technology have enabled the creation of 3D retinal organoids, which closely mimic the structure and function of the human retina. These organoids provide a valuable platform for studying retinal development, modeling diseases, and testing potential therapies. By understanding the molecular mechanisms underlying eye formation and disease progression, researchers can identify and develop targeted treatments. Retinal organoids hold the promise of revolutionizing the field of regenerative medicine and vision research, offering hope for restoring vision and improving the lives of individuals affected by retinal diseases.
Source: IntechOpen eBooks
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Funder: Royan Institute
OpenAlex ID: W4407154348