Work

Proximal bowel obstruction caused by high-grade duodenal adenocarcinoma: A rare case

Year: 2025

Type: article

Abstract: Introduction: Duodenal adenocarcinoma is an exceptionally rare malignancy, constituting less than 0.5% of all gastrointestinal cancers. Its nonspecific symptoms often lead to delayed diagnosis and advanced disease at presentation. Case presentation: A 64-year-old female presented with epigastric pain, nausea, and biliary vomiting. Imaging revealed a proximal small bowel obstruction, and endoscopy identified a high-grade duodenal adenocarcinoma. The patient underwent a successful duodenojejunectomy, side-to-side anastomosis, and lymphadenectomy. Discussion: Post-operative recovery was uneventful, leading to discharge in stable condition. This case underscores the importance of considering duodenal adenocarcinoma in differential diagnoses for small bowel obstruction and highlights the effectiveness of surgical management. Conclusion: Duodenal adenocarcinoma, though rare, should be considered in patients with small bowel obstruction. Early diagnosis and prompt surgical intervention are crucial for favorable outcomes.

Source: Annals of Medicine and Surgery

DOI: 10.1097/ms9.0000000000002983

Authors: Rana Ibrahim, Mohammad Yassine, Zakaria Dika

Institution: Saint George Hospital

Language: English

Topic: Gastric Cancer Management and Outcomes

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,850