Fluorescein Angiography as a Surrogate Marker of Disease Activity in Susac Syndrome
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: To evaluate the sensitivity of fluorescein angiography (FA) in detecting disease activity in Susac syndrome. METHODS: We conducted a blinded analysis of all FA, brain MRI, and audiogram examinations performed throughout the follow-up of patients with Susac syndrome. RESULTS: < 0.05). DISCUSSION: FA, particularly arterial leakage, demonstrated the highest sensitivity in detecting disease activity and may be a valuable tool for treatment management in Susac syndrome. Future studies with larger samples should aim to identify the optimal threshold of FA changes associated with an increased risk of relapse.
Institutions: Assistance Publique Hôpitaux de Marseille, Hôpital de la Timone, Hôpital Européen, Centre Hospitalier de Redon, Centre Hospitalier d'Angoulême, Centre Hospitalier d'Arras, Centre National de la Recherche Scientifique, Aix-Marseille Université, Centre de Résonance Magnétique Biologique et Médicale
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,450
OpenAlex ID: W4407162228