Dupilumab for treatment of primary cutaneous amyloidosis in adults: two case reports and literature review
Year: 2025
Type: article
Study design: Case Report
Abstract: Lichenoid amyloidosis (LA), a subtype of primary cutaneous amyloidosis (PCA), is featured by intensely pruritic, hyperkeratotic papules which lacks standardized treatment. Dupilumab, a human monoclonal antibody targeting for interleukin (IL)-4/13 receptor α chain, is widely applied in type 2 inflammation diseases treatment. This article reported two cases of refractory LA successfully treated with dupilumab and reviewed publications reporting dupilumab treatment for PCA.
Source: Frontiers in Medicine
Authors: Feiying Guo, Huajie Zhong, Yuan Wu, Xue Xu, Jiarong Tan, Qiang Zhou, Shunli Tang
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4407181326