Work

Paper Electrochemical Sensor Utilizing Nano Ag‐Decorated Cu2O Nanoparticles for Ascorbic Acid Detection in Tablets

Year: 2025

Type: article

Abstract: The accurate and selective detection of vitamins are very much needed in the food, and pharmaceutical industries and health care. In this study, a new sustainable disposable electrochemical platform was fabricated with nano silver/Cu2O composite (nAg/Cu2O) for sensing ascorbic acid (vitamin C). The modified electrode exhibited reduced resistance to charge transfer and improved electro active area. The analyte displayed excellent electrochemical activity on the surface of nAg/Cu2O modified paper electrode and showed a concentration‐dependent response between 0.05 to 500 μM with a detection limit (S/N=3), 0.04 μM. Furthermore, the anti‐interference studies revealed that the nAg/Cu2O nanocomposites have high selectivity towards ascorbic acid. Notably, the sensor based on nAg/Cu2O showed exceptional stability and reproducibility, with a relative standard deviation for peak currents measuring approximately 7 % or less while testing for a week of time. The real‐world application and analytical performance was realized by identifying ascorbic acid in commercial vitamin C tablets with satisfactory results.

Source: Analysis & Sensing

DOI: 10.1002/anse.202400118

Authors: A. Venkadesh, Anumol Mathew, Thayyil K. Fahmeeda, J. Sonia, B. N. Kumara, K. Sudhakara Prasad

Institutions: Yenepoya University, Yenepoya Research Centre

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: bronze

Funders: Department of Biotechnology, Ministry of Science and Technology, India, Indian Council of Medical Research, Biotechnology Industry Research Assistance Council

Awards: G323294840, G4918206637