Work

Using an acellular dermal matrix as a neuroprotective wrap-around for treating recurrent nerve entrapment syndromes: a proof of concept

Year: 2025

Type: article

Abstract: Recurrent nerve entrapment syndrome is a well-known complication in peripheral nerve surgery that often leads to multiple reoperations and increases the risk of unfavorable outcomes due to scarring. In our outpatient clinic, we found two patients with recurrent nerve entrapment syndrome with significant symptoms such as complete sensory loss and chronic pain who were willing to undergo re-exploration of their entrapped nerves and cover them with a human acellular dermal matrix (ADM) as a protective shield against recurrence. Both patients had complete recovery of the nerve entrapment syndrome with satisfactory clinical results. The use of a human ADM appears to be a promising tool for recurrent nerve entrapment surgery without adding morbidity to the procedure.

Source: Cell and Tissue Banking

DOI: 10.1007/s10561-025-10159-2

Authors: Till Wagner, Dietmar J. O. Ulrich

Institutions: Radboud University Nijmegen, Radboud University Medical Center

Language: English

Topic: Peripheral Nerve Disorders

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,990