Year: 2025
Type: article
Abstract: The landscape of nuclear medicine is undergoing a profound transformation, driven by the rapid evolution of radiopharmaceuticals. These innovative agents are redefining the boundaries of diagnostic imaging and targeted therapy, offering unprecedented opportunities for precision medicine. This comprehensive review article provides a cutting-edge overview of the emerging trends and applications of radiopharmaceuticals in diagnostic imaging and therapy. We delve into the latest advancements in radiopharmaceutical design, synthesis, and application, including the development of novel isotopes, peptides, and antibodies. The article highlights the growing importance of Theranostics, immuno-PET, and alpha-particle therapy in cancer diagnosis and treatment, as well as their potential applications in neurology, cardiology, and infectious diseases. Furthermore, we examine the challenges and future directions in radiopharmaceutical development, including the need for standardized manufacturing processes, improved regulatory frameworks, and enhanced radiation safety measures. We also discuss the role of artificial intelligence, machine learning, and big data analytics in accelerating the development and application of radiopharmaceuticals. This review article aims to provide a roadmap for the future development and application of radiopharmaceuticals in diagnostic imaging and therapy, highlighting the vast potential of these innovative agents to revolutionize the field of nuclear medicine and improve patient outcomes. Key words: Radiopharmaceuticals, Nuclear medicine, Diagnostic imaging, Therapy, Oncology, Neurology, Cardiology, Infectious diseases, Theranostics, Immuno-PET, Alpha-particle therapy, Precision medicine, Personalized medicine, Artificial intelligence, Machine learning, big data analytics, Radiopharmaceutical development, Regulatory frameworks, Radiation safety, Molecular imaging.
Authors: Sameer Ahmad Ganaie, Ruqiya Ramzan, Mubashir Habib
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4407186414