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An Unusual Case of Intrahepatic Stone Masquerading as Cholangiocarcinoma

Year: 2025
Type: article
Study design: Case Report
Abstract: A cancer of the biliary tree, cholangiocarcinoma (CCA) often presents with painless jaundice, right upper quadrant abdominal pain, and unintended weight loss. Serologic testing to include cancer antigen 19-9 (CA 19-9) is elevated in CCA but can also be elevated in inflammatory processes in the biliary system. Diagnosis is difficult and even with advanced imaging techniques false-positives may occur. We present a case of a patient with elevated CA 19-9 and biliary stricture concerning for CCA but was due to hepatic stone. It demonstrates the challenge of correctly diagnosing CCA and an instance of nonmalignant elevation of CA 19-9.
Authors: Alexander S. Williams, Michael A. Sikes, Scott Liu
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4407191530
FWCI:
Cites: 9
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Related to: 10