Work

Protective effects of Pyrogallol and Caffeic acid against Fe2+ -Ascorbate-induced oxidative stress in the wistar rats liver: An in vitro study

Year: 2025

Type: article

Abstract: values for DPPH free radicals for pyrogallol and caffeic acid were determined to be 76.26 μg/mL and 106.31 μg/mL, respectively. Notably, pyrogallol and caffeic acid exhibited higher antioxidant activity in all assays than catechin. In most assays (DPPH, Lipid peroxidation, and PCO) and at high concentrations (50 and 100 μg/mL), the antioxidative stress activity of pyrogallol was higher than that of caffeic acid. In conclusion, this study's results suggest that these compounds can potentially ameliorate diseases associated with oxidative stress.

Source: Heliyon

DOI: 10.1016/j.heliyon.2025.e42518

Authors: Seifollah Bahramikia, Nasrin Shirzadi, Vali Akbari

Institution: Lorestan University

Language: English

Topic: Phytochemicals and Antioxidant Activities

Subfield: Biochemistry

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,270