Work

A generalization of cell survival models via fractional approach

Year: 2025

Type: article

Abstract: This study investigates the relationship between radiation dose and the number of surviving cells as a result of radiation treatment by revisiting and extending linear, quadratic, and linear-quadratic cell survival models using fractional calculus. The generalized version of these models, called as fractional cell survival model, offers a deeper insight into the mechanisms underlying cell survival. This model shows a good harmony with the experimental findings, and it is also generalized the standard models when the fractional derivative orders are equal to 1. This new approach not only makes cell survival predictions more accurate, but also gives us a better understanding of how radiation affects cells and how they respond.

Source: Physica Scripta

DOI: 10.1088/1402-4896/adb356

Authors: Mürsel Şen, Abdullah Engin Çalık, Ibrahim Senturk, Hüseyin Şirin

Institutions: Ege University, Milli Savunma Üniversitesi, Turkish Air Force Academy, Izmir Biomedicine and Genome Center

Language: English

Topic: Fractional Differential Equations Solutions

Subfield: Modeling and Simulation

Field: Mathematics

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $2,400

OpenAlex ID: W4407209519

FWCI: 2.245

Cites: 45

Cited by: 3

Related to: 10