Work

Synthesis of 4-Substituted 3-Nitrophenyl Carbonyl Compounds from Benzyl Alcohols

Year: 2024

Type: article

Abstract: A procedure has been developed for the synthesis of 4-R-3-nitrophenyl carbonyl compounds via tandem oxidation–nitration of benzyl alcohols. The proposed one-pot procedure makes it possible to obtain the target products in good yields under mild conditions using stable commercially available reagents. The major requirement to the substrate structure is the presence of a mesomeric donor substituent at the para position with respect to the hydroxymethyl group.

Source: Russian Journal of Organic Chemistry

DOI: 10.1134/s1070428024120054

Authors: D. A. Kazantsev, A. A. Denisov, A. V. Pestov

Institutions: Russian Academy of Sciences, Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ural Federal University

Language: English

Topic: Oxidative Organic Chemistry Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Russian Science Foundation

OpenAlex ID: W4407212217

FWCI:

Cites: 10

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Related to: 10