Work

Development of ASGR-Mediated Hepatocyte-Targeting Cytotoxic Drug Conjugates with CTSB-Cleavable Linkers Incorporating Succinimide and Succinic Acid Monoamide

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c02232

Authors: Jingsheng Jiang, Sigang Jian, Feifei Lin, Zhuo Zhang, Qianqian Shen, Guozhang Long, Biyu Yang, Junzhen Lin, Yanfen Fang, Jian Ding, Jia Liu, Yi Chen, Youhong Hu

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, ShanghaiTech University, Nanjing University of Chinese Medicine, Xinjiang Technical Institute of Physics & Chemistry

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Science and Technology Commission of Shanghai Municipality, Program of Shanghai Academic Research Leader

Awards: G270004384, G8408817410, G8771222309

OpenAlex ID: W4407238209

FWCI: 0.376

Cites: 41

Cited by: 2

Related to: 10