Year: 2025
Type: article
Study design: Case Report
Abstract: Hyperlipoproteinemia is a very rare condition in a neonate and its mechanism includes lipoprotein molecular defect, lipoprotein lipase deficiency, or lipoprotein receptor defect. The common ones are familial combined hyperlipidemias, familial & polygenic hypercholesterolemia and familial hypertriglyceridemia. Usually, the detection is by accidental observation of milky blood while sampling for non-specific symptoms. Hyperlipoproteinemia can cause acute pancreatitis and early-onset cardiovascular disease if left untreated. Here we are reporting the case of a 25-day-old baby who presented with blood in stools. Physical examination was normal. Incidentally, it was found that the blood was highly viscous and milky. Complete lipid profile done suggested familial combined hyperlipidemia. The baby was started on Gemfibrozil (20 mg/kg twice daily) and continued on exclusive breast feeds along with the addition of medium chain triglyceride oil and multivitamins. Lipoprotein levels normalized within 5 months. This condition requires lifelong follow up.
Source: Indian Journal of Child Health
Authors: Aishwarya Venugopal, Aswathy Rahul, Radhika Sujatha, Prakash Duraisamy, A V Anupriya, Nikhil Kumar, Meghna Nema
Institution: Government Medical College
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407242793