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Human Tendon‐on‐a‐Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis (Adv. Healthcare Mater. 4/2025)

Year: 2025

Type: article

Abstract: Tendon-on-a-Chip A novel human Tendon-on-a-Chip model replicates aspects of the myofibroblast microenvironment in peritendinous adhesions. This chip sheds light on cellular and molecular crosstalk between immune cells, endothelial cells, and myofibroblasts, offering a powerful tool for drug testing and de-risking drug development for fibrotic diseases. More details can be found in article 2403116 by Hani A. Awad and co-workers.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.202570024

Authors: Raquel E. Ajalik, Isabelle Linares, Rahul G. Alenchery, Victor Z. Zhang, Terry W. Wright, Benjamin L. Miller, James L. McGrath, Hani A. Awad

Language: English

Topic: Tendon Structure and Treatment

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4407246432

FWCI:

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