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Health‐State Utility Values in Patients Affected by Flaccid and Non‐Flaccid Facial Paralysis

Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: The primary goal of this study was to measure health-state utility values (HUVs) in patients with facial paralysis before and after treatment. A secondary objective was to compare these values with those of other chronic diseases and currently available treatments. STUDY DESIGN: A retrospective chart review. SETTING: A tertiary medical center. METHODS: Adults with flaccid and non-flaccid facial paralysis were included. Baseline demographics, medical comorbidities, facial paralysis history, treatment details, and disease-specific quality-of-life scores were collected. Utility values were derived using the Short-Form 6D health index at baseline and after treatment. RESULTS: The mean baseline Short-Form 6D utility value for patients with facial paralysis (n = 134) was 0.73 (± 0.14) (95% confidence interval [CI]: 0.71-0.75). Baseline utility values significantly correlated with disease-specific quality of life as measured by the Facial Clinimetric Evaluation Scale (r = 0.400; P < .001), but not with Sunnybrook Facial Grading Scale or Synkinesis Assessment Questionnaire scores. Post-treatment utility values showed a mean improvement of 0.03 (95% CI: -0.01 to 0.08; P = .14) in the overall cohort. The flaccid group showed a greater average improvement compared to the non-flaccid group (0.05 [± 0.17] vs 0.02 [± 0.17]; P = .62). CONCLUSION: Patients with flaccid and non-flaccid facial paralysis reported HUVs that were significantly lower than the US population norm. Treatment improved utility values in both groups. These findings provide initial data for future cost-effectiveness analyses of surgical and non-surgical treatment options for facial paralysis.
DOI: 10.1002/ohn.1163
Language: English
Subfield: Neurology
Field: Medicine
Open Access status: bronze
OpenAlex ID: W4407255395
FWCI: 1.09
Cites: 45
Cited by: 2
Related to: 10