Comparative hemodynamic responses to upright and recumbent cycling in patients with exercise intolerance
Year: 2025
Type: article
Abstract: Introduction: Understanding the influence of body position on cardiovascular responses during exercise is crucial for precise diagnostic and therapeutic strategies, particularly in patients with exercise intolerance. Aim: This study aims to compare the hemodynamic responses to exercise in upright and recumbent cycling positions in patients with exercise intolerance. Methods: A cross-over study design was employed, enrolling 21 patients for right heart catheterization during exercise in both upright and recumbent positions. Hemodynamic variables were measured at rest and across various exercise intensities. Results: Significant differences were observed in right atrial pressure (RAP), mean pulmonary artery pressure (mPAP), and pulmonary artery wedge pressure (PAWP) between upright and recumbent positions. Upright exercise revealed lower values of RAP, mPAP, and PAWP, indicating distinct hemodynamic profiles. Conclusion: Body position significantly affects cardiovascular dynamics during exercise, providing valuable insights for diagnosing and managing exercise intolerance.
Authors: Arif Albulushi, Faisal Al Harthi, Gamal Aly, Yahya Al-Wahshi, Mohammed H. El-Deeb
Institutions: Royal Hospital, University of Nebraska Medical Center
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4407261823