Work

Respiratory Diphtheria in a 16-Year-Old Who Developed Multiple Life-Threatening Complications

Year: 2025

Type: article

Abstract: Diphtheria is a contagious disease with high mortality. Although the global prevalence has been decreasing, the immigration of certain populations with suboptimal vaccination coverage has contributed to its resurgence in developed countries. We report a 16-year-old Afghan male with acute respiratory distress and life-threatening complications, including fulminant myocarditis with cardiac arrhythmias and neurologic complications. This case highlights the significance of optimal vaccination coverage, especially the vaccination status of migrants. This paper serves as a reminder of diphtheria's systemic impact and underscores the need for a multidisciplinary approach to respiratory diphtheria management. Vigilant monitoring, prompt immunoglobulin and antibiotic administration, and supportive care all play pivotal roles in enhancing patient outcomes and reducing mortality risks.

Source: Journal of the American College of Emergency Physicians Open

DOI: 10.1016/j.acepjo.2025.100043

Authors: Thomas Boisdenghien, Juliette Genot, Mahmoud Kaabour, Axel Derwa, Sergio Rizzi, Marie Belleflamme

Institutions: Cliniques Universitaires Saint-Luc, UCLouvain, Clinique Saint Jean

Language: English

Topic: Diphtheria, Corynebacterium, and Tetanus

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,600