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An unusual mediastinal giant parathyroid adenoma: A rare case report

Year: 2025

Type: article

Abstract: Parathyroid adenoma is the most common cause of primary hyperparathyroidism. Giant parathyroid adenoma is considered a rare subtype of parathyroid adenomas that weigh more than 3.5 grams and cause a small number of adenoma related hyperparathyroidism. We present a case of 68-year-old asymptomatic male patient who had hypercalcemia and markedly high parathyroid hormone level on routine blood testing. Radiological investigations demonstrated a large mediastinal mass that showed peripheral high uptake on sestamibi scan. Histopathology confirmed the diagnosis of giant parathyroid adenoma. Giant parathyroid adenomas can have an atypical radiological appearance and present as a mediastinal mass that resembles other mediastinal masses, making it important to include in the list of possible diagnoses.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.01.068

Authors: Ahmad Huneity, Yaman M. Alahmad, Issam Al Bozom, Abdelkareem Alhyari, Ayoub Alaoud, Rajendra Kumar

Institution: Hamad Medical Corporation

Language: English

Topic: Parathyroid Disorders and Treatments

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600